Here, we demonstrate that conolidine, a organic analgesic alkaloid used in conventional Chinese drugs, targets ACKR3, therefore providing additional evidence of a correlation in between ACKR3 and pain modulation and opening alternate therapeutic avenues for the treatment of Long-term agony. The first asymmetric full synthesis of conolidine was created https://isconolidineanopiate98549.pointblog.net/new-step-by-step-map-for-conolidine-75213229